What is mupirocin topical? Mupirocin is an antibiotic that prevents bacteria from growing on your skin. Mupirocin topical (for use on the skin) is used to treat skin infections such as impetigo (IM-pe-TYE-go) or a "Staph" infection of the skin. Mupirocin topical may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use mupirocin topical if you are allergic to mupirocin. To make sure mupirocin topical is safe for you, tell your doctor if you have ever had: kidney disease. Do not use mupirocin topical on a child without medical advice. The cream should not be used on a child younger than 3 months old. The ointment may be used on a child as young as 2 months old. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. It is not known whether mupirocin topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. If you apply this medicine to your breast or nipple, wash the areas thoroughly before nursing your baby. How should I use mupirocin topical? Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Do not take by mouth. Topical medicine is for use only on the skin. If this medicine gets in your eyes, nose, or mouth, rinse with water. Wash your hands before and after applying mupirocin topical. Clean and dry the affected skin area. Use a cotton swab or gauze pad to apply a small amount of mupirocin topical as directed. Do not spread mupirocin topical over large areas of skin. Mupirocin topical is usually applied 3 times per day for 10 days. Use only a small amount of the medicine. Use a sterile gauze pad to cover the treated skin. Do not cover treated areas with a bandage, plastic wrap, or other covering that does not allow air to circulate. Call your doctor if your symptoms do not improve within 3 to 5 days, or if your skin condition gets worse. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Store at room temperature away from moisture and heat. Do not freeze. Keep the medicine tube tightly closed when not in use. What happens if I miss a dose? Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? An overdose of mupirocin topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. What should I avoid while using mupirocin topical? Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to. Avoid getting mupirocin topical in your eyes, mouth, or nose. A separate product called mupirocin nasal is made for use in the nose. Mupirocin topical is for use only on the skin. Avoid using other medications on the areas you treat with mupirocin topical unless your doctor tells you to. Mupirocin topical side effects Get emergency medical help if you have signs of an allergic reaction: hives; dizziness, fast or pounding heartbeats; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; severe itching, rash, or other irritation of treated skin; unusual skin blistering or peeling; or any signs of a new skin infection. Common side effects may include: burning, stinging; itching; or pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Mupirocin topical dosing information Usual Adult Dose for Secondary Cutaneous Bacterial Infections: Topical cream: Apply a small amount to the affected area 3 times a day for 10 days. Use: For the treatment of secondarily infected traumatic skin lesions (up to 10 cm in length or 100 cm2 in area) due to susceptible strains of Staphylococcus aureus and Streptococcus pyogenes Usual Adult Dose for Nasal Carriage of Staphylococcus aureus: Nasal ointment: Apply about one-half of the tube contents into 1 nostril and the other half into the other nostril twice a day (morning and evening). Duration of therapy: 5 days Use: For the eradication of nasal colonization with methicillin-resistant S aureus (MRSA) in patients and healthcare workers as part of a comprehensive infection control program to reduce risk of MRSA infection among high-risk patients during institutional outbreaks of MRSA infections Usual Adult Dose for Impetigo: Topical ointment: Apply a small amount to the affected area 3 times a day. Use: For the topical treatment of impetigo due to S aureus and S pyogenes Usual Pediatric Dose for Secondary Cutaneous Bacterial Infections: 3 months or older: Topical cream: Apply a small amount to the affected area 3 times a day for 10 days. Use: For the treatment of secondarily infected traumatic skin lesions (up to 10 cm in length or 100 cm2 in area) due to susceptible strains of S aureus and S pyogenes Usual Pediatric Dose for Nasal Carriage of Staphylococcus aureus: 12 years or older: Nasal ointment: Apply about one-half of the tube contents into 1 nostril and the other half into the other nostril twice a day (morning and evening). Duration of therapy: 5 days Use: For the eradication of nasal colonization with MRSA in patients and healthcare workers as part of a comprehensive infection control program to reduce risk of MRSA infection among high-risk patients during institutional outbreaks of MRSA infections Usual Pediatric Dose for Impetigo: 2 months or older: Topical ointment: Apply a small amount to the affected area 3 times a day. Use: For the topical treatment of impetigo due to S aureus and S pyogenes   What other drugs will affect mupirocin topical? It is not likely that other drugs you take orally or inject will have an effect on topically applied mupirocin. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

What is mycophenolate mofetil? Mycophenolate mofetil is used with other medicines to prevent organ transplant rejection. Mycophenolate mofetil is for use with a liver or heart transplant in adults. mycophenolate mofetil is for use with a kidney transplant in adults and children at least 3 months old. Mycophenolate mofetil may also be used for purposes not listed in this medication guide. Warnings This medicine can cause a miscarriage or birth defects when used during pregnancy. Both men and women should use effective birth control to prevent pregnancy during and shortly after treatment with mycophenolate mofetil. Using mycophenolate mofetil may increase your risk of cancer, serious infections, or kidney transplant failure. Call your doctor right away if you have symptoms such as: fever, swollen glands, weight loss, vomiting or diarrhea, painful urination, a new skin lesion, any change in your mental state, weakness on one side of your body, or pain near your transplanted kidney. Before taking this medicine You should not use mycophenolate mofetil if you are allergic to mycophenolate mofetil, mycophenolic acid, or polysorbate 80. Talk with your doctor about the risks and benefits of mycophenolate mofetil. This medicine may increase your risk of cancer, serious or fatal infections, or a viral infection that can cause kidney transplant failure. Tell your doctor if you have ever had: a stomach ulcer or problems with digestion; diabetes; hepatitis B or C or other viral infection (may become active or get worse while you are using mycophenolate mofetil); phenylketonuria, or PKU (the liquid form of this medicine may contain phenylalanine); or a rare inherited enzyme deficiency such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome. This medicine can cause a miscarriage or birth defects, especially during the first 3 months of pregnancy. You will need to have a negative pregnancy test before and during treatment with this medicine. If you are able to get pregnant, you must use specific forms of birth control to prevent pregnancy while using mycophenolate mofetil, and for at least 6 weeks after your last dose. Sexually active men and their partners should use effective contraception during treatment and for at least 90 days after the last dose. Mycophenolate mofetil can make birth control pills less effective. Ask your doctor about using an additional barrier form of birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy. You do not need to use additional birth control if you use an intrauterine device (IUD), if you have had a tubal ligation, or if your sexual partner has had a vasectomy. This medicine comes with patient instructions about the most effective non-hormonal forms of birth control to use. Follow these directions carefully. Ask your doctor if you have any questions. If a pregnancy occurs during treatment, do not stop taking mycophenolate mofetil. Call your doctor for instructions. Also call the Mycophenolate Pregnancy Registry (1-800-617-8191). Mycophenolate mofetil is sometimes given to pregnant women. Your doctor will decide whether you should use this medicine if you are unable to use other needed transplant medications. You should not breastfeed while using mycophenolate mofetil. How should I use mycophenolate mofetil? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. You must remain under the care of a doctor while you are using mycophenolate mofetil. Mycophenolate mofetil injection is given as an infusion into a vein. A healthcare provider will give you this injection. Take oral mycophenolate mofetil on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow the capsule or tablet whole and do not crush, chew, break, or open it. Tell your doctor if you have trouble swallowing a tablet or capsule. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Shake the oral suspension (liquid) before you measure a dose. Use only the dosing syringe provided with this medicine. Mycophenolate mofetil (CellCept) and mycophenolic acid (Myfortic) are not absorbed equally in the body. Avoid medication errors by using only the brand, form, and strength of this medicine that your doctor has prescribed. You will need frequent medical tests. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Throw away any unused liquid that is older than 60 days. The liquid medicine may also be stored in the refrigerator. Do not freeze. What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 2 hours. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using mycophenolate mofetil? Avoid driving or hazardous activity until you know how mycophenolate mofetil will affect you. Your reactions could be impaired. Mycophenolate mofetil can make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Do not receive a "live" vaccine while using mycophenolate mofetil. The vaccine may not work as well and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine. You must not donate blood or sperm while using this medicine, and for at least 6 weeks (for blood) or 90 days (for sperm) after your last dose. Mycophenolate mofetil side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Mycophenolate mofetil may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly. Mycophenolate mofetil affects your immune system and may increase your risk of cancer or serious infection. Call your doctor right away if you have: fever of 100.5 degrees F or higher, swollen glands, painful mouth sores, cold or flu symptoms, headache, ear pain; stomach pain, vomiting, diarrhea, weight loss; weakness on one side of your body, loss of muscle control; confusion, thinking problems, loss of interest in things that normally interest you; pain around the transplanted kidney; pain or burning when you urinate; dark urine, jaundice (yellowing of the skin or eyes); tingly or painful blistering rash on one side of your body; swelling, warmth, redness, or oozing around a skin wound; or a new skin lesion, or a mole that has changed in size or color. Also call your doctor at once if you have: bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath. Common side effects may include: stomach pain, nausea, vomiting, diarrhea, constipation; swelling in your ankles or feet; rash; headache, dizziness, tremors; fever, sore throat, cold symptoms, or other signs of infections; abnormal blood tests, high blood sugar; pain anywhere in your body; low blood cell counts; or high or low blood pressure, fast heart rate. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Mycophenolate mofetil dosing information Usual Adult Dose for Organ Transplant -- Rejection Prophylaxis: -RENAL TRANSPLANTATION: 1 g orally or IV 2 times a day (2 gm per day); [in clinical trials, 1.5 g orally or IV 2 times a day (3 gm per day) was used effectively, however, the safety profile for 3 gm a day was lower] -CARDIAC TRANSPLANTATION: 1.5 g orally or IV 2 times a day (3 gm per day) -HEPATIC TRANSPLANTATION: 1.5 gm orally or 1 gm IV 2 times a day (3 gm per day orally or 2 gm per day IV) Comments: -This drug should be used concomitantly with cyclosporine and corticosteroids. -The IV formulation should be administered over no less than 2 hours. -IV administration is recommended in patients unable to take oral medication; oral administration should be initiated as soon as possible. Usual Geriatric Dose for Organ Transplant -- Rejection Prophylaxis: -RENAL TRANSPLANTATION: 1 g orally or IV 2 times a day (2 gm per day) -CARDIAC TRANSPLANTATION: 1.5 g orally or IV 2 times a day (3 gm per day) -HEPATIC TRANSPLANTATION: 1.5 gm orally or 1 gm IV 2 times a day (3 gm per day orally or 2 gm per day IV) Comments: -This drug should be used concomitantly with cyclosporine and corticosteroids. -The IV formulation should be administered over no less than 2 hours. -IV administration is recommended in patients unable to take oral medication; oral administration should be initiated as soon as possible. Usual Pediatric Dose for Organ Transplant -- Rejection Prophylaxis: -RENAL TRANSPLANTATION: 3 months to 18 years of age: Oral Suspension: 600 mg/m2 orally 2 times a day up to a maximum of 2 grams per day -Pediatric patients with a body surface area of 1.25 to 1.5 m2 may be dosed with the oral capsules at 750 mg orally 2 times a day (1.5 g per day) -Pediatric patients with a body surface area greater than 1.5 m2 may be dosed with the oral capsules at 1 g orally 2 times a day (2 g per day) Comments: -This drug should be used concomitantly with cyclosporine and corticosteroids. -The IV formulation should be administered over no less than 2 hours.-IV administration is recommended in patients unable to take oral medication; oral administration should be initiated as soon as possible.   What other drugs will affect mycophenolate mofetil? If you take sevelamer or an antacid, take your oral mycophenolate mofetil dose 2 hours before you take these other medicines. Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor about all your current medicines. Many drugs can affect mycophenolate mofetil, especially: azathioprine; cholestyramine; antiviral medicine--acyclovir, ganciclovir, valacyclovir, valganciclovir; an antibiotic--amoxicillin, ciprofloxacin, metronidazole, norfloxacin, rifampin, sulfa drugs; or a stomach acid reducer--esomeprazole, lansoprazole, omeprazole, Nexium, Prevacid, Prilosec, Protonix, and others. This list is not complete and many other drugs may affect mycophenolate mofetil. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is mycophenolate mofetil? Mycophenolate mofetil is used with other medicines to prevent organ transplant rejection. Mycophenolate mofetil is for use with a liver or heart transplant in adults. mycophenolate mofetil is for use with a kidney transplant in adults and children at least 3 months old. Mycophenolate mofetil may also be used for purposes not listed in this medication guide. Warnings This medicine can cause a miscarriage or birth defects when used during pregnancy. Both men and women should use effective birth control to prevent pregnancy during and shortly after treatment with mycophenolate mofetil. Using mycophenolate mofetil may increase your risk of cancer, serious infections, or kidney transplant failure. Call your doctor right away if you have symptoms such as: fever, swollen glands, weight loss, vomiting or diarrhea, painful urination, a new skin lesion, any change in your mental state, weakness on one side of your body, or pain near your transplanted kidney. Before taking this medicine You should not use mycophenolate mofetil if you are allergic to mycophenolate mofetil, mycophenolic acid, or polysorbate 80. Talk with your doctor about the risks and benefits of mycophenolate mofetil. This medicine may increase your risk of cancer, serious or fatal infections, or a viral infection that can cause kidney transplant failure. Tell your doctor if you have ever had: a stomach ulcer or problems with digestion; diabetes; hepatitis B or C or other viral infection (may become active or get worse while you are using mycophenolate mofetil); phenylketonuria, or PKU (the liquid form of this medicine may contain phenylalanine); or a rare inherited enzyme deficiency such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome. This medicine can cause a miscarriage or birth defects, especially during the first 3 months of pregnancy. You will need to have a negative pregnancy test before and during treatment with this medicine. If you are able to get pregnant, you must use specific forms of birth control to prevent pregnancy while using mycophenolate mofetil, and for at least 6 weeks after your last dose. Sexually active men and their partners should use effective contraception during treatment and for at least 90 days after the last dose. Mycophenolate mofetil can make birth control pills less effective. Ask your doctor about using an additional barrier form of birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy. You do not need to use additional birth control if you use an intrauterine device (IUD), if you have had a tubal ligation, or if your sexual partner has had a vasectomy. This medicine comes with patient instructions about the most effective non-hormonal forms of birth control to use. Follow these directions carefully. Ask your doctor if you have any questions. If a pregnancy occurs during treatment, do not stop taking mycophenolate mofetil. Call your doctor for instructions. Also call the Mycophenolate Pregnancy Registry (1-800-617-8191). Mycophenolate mofetil is sometimes given to pregnant women. Your doctor will decide whether you should use this medicine if you are unable to use other needed transplant medications. You should not breastfeed while using mycophenolate mofetil. How should I use mycophenolate mofetil? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. You must remain under the care of a doctor while you are using mycophenolate mofetil. Mycophenolate mofetil injection is given as an infusion into a vein. A healthcare provider will give you this injection. Take oral mycophenolate mofetil on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow the capsule or tablet whole and do not crush, chew, break, or open it. Tell your doctor if you have trouble swallowing a tablet or capsule. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Shake the oral suspension (liquid) before you measure a dose. Use only the dosing syringe provided with this medicine. Mycophenolate mofetil (CellCept) and mycophenolic acid (Myfortic) are not absorbed equally in the body. Avoid medication errors by using only the brand, form, and strength of this medicine that your doctor has prescribed. You will need frequent medical tests. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Throw away any unused liquid that is older than 60 days. The liquid medicine may also be stored in the refrigerator. Do not freeze. What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 2 hours. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using mycophenolate mofetil? Avoid driving or hazardous activity until you know how mycophenolate mofetil will affect you. Your reactions could be impaired. Mycophenolate mofetil can make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Do not receive a "live" vaccine while using mycophenolate mofetil. The vaccine may not work as well and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine. You must not donate blood or sperm while using this medicine, and for at least 6 weeks (for blood) or 90 days (for sperm) after your last dose. Mycophenolate mofetil side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Mycophenolate mofetil may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly. Mycophenolate mofetil affects your immune system and may increase your risk of cancer or serious infection. Call your doctor right away if you have: fever of 100.5 degrees F or higher, swollen glands, painful mouth sores, cold or flu symptoms, headache, ear pain; stomach pain, vomiting, diarrhea, weight loss; weakness on one side of your body, loss of muscle control; confusion, thinking problems, loss of interest in things that normally interest you; pain around the transplanted kidney; pain or burning when you urinate; dark urine, jaundice (yellowing of the skin or eyes); tingly or painful blistering rash on one side of your body; swelling, warmth, redness, or oozing around a skin wound; or a new skin lesion, or a mole that has changed in size or color. Also call your doctor at once if you have: bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath. Common side effects may include: stomach pain, nausea, vomiting, diarrhea, constipation; swelling in your ankles or feet; rash; headache, dizziness, tremors; fever, sore throat, cold symptoms, or other signs of infections; abnormal blood tests, high blood sugar; pain anywhere in your body; low blood cell counts; or high or low blood pressure, fast heart rate. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Mycophenolate mofetil dosing information Usual Adult Dose for Organ Transplant -- Rejection Prophylaxis: -RENAL TRANSPLANTATION: 1 g orally or IV 2 times a day (2 gm per day); [in clinical trials, 1.5 g orally or IV 2 times a day (3 gm per day) was used effectively, however, the safety profile for 3 gm a day was lower] -CARDIAC TRANSPLANTATION: 1.5 g orally or IV 2 times a day (3 gm per day) -HEPATIC TRANSPLANTATION: 1.5 gm orally or 1 gm IV 2 times a day (3 gm per day orally or 2 gm per day IV) Comments: -This drug should be used concomitantly with cyclosporine and corticosteroids. -The IV formulation should be administered over no less than 2 hours. -IV administration is recommended in patients unable to take oral medication; oral administration should be initiated as soon as possible. Usual Geriatric Dose for Organ Transplant -- Rejection Prophylaxis: -RENAL TRANSPLANTATION: 1 g orally or IV 2 times a day (2 gm per day) -CARDIAC TRANSPLANTATION: 1.5 g orally or IV 2 times a day (3 gm per day) -HEPATIC TRANSPLANTATION: 1.5 gm orally or 1 gm IV 2 times a day (3 gm per day orally or 2 gm per day IV) Comments: -This drug should be used concomitantly with cyclosporine and corticosteroids. -The IV formulation should be administered over no less than 2 hours. -IV administration is recommended in patients unable to take oral medication; oral administration should be initiated as soon as possible. Usual Pediatric Dose for Organ Transplant -- Rejection Prophylaxis: -RENAL TRANSPLANTATION: 3 months to 18 years of age: Oral Suspension: 600 mg/m2 orally 2 times a day up to a maximum of 2 grams per day -Pediatric patients with a body surface area of 1.25 to 1.5 m2 may be dosed with the oral capsules at 750 mg orally 2 times a day (1.5 g per day) -Pediatric patients with a body surface area greater than 1.5 m2 may be dosed with the oral capsules at 1 g orally 2 times a day (2 g per day) Comments: -This drug should be used concomitantly with cyclosporine and corticosteroids. -The IV formulation should be administered over no less than 2 hours.-IV administration is recommended in patients unable to take oral medication; oral administration should be initiated as soon as possible.   What other drugs will affect mycophenolate mofetil? If you take sevelamer or an antacid, take your oral mycophenolate mofetil dose 2 hours before you take these other medicines. Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor about all your current medicines. Many drugs can affect mycophenolate mofetil, especially: azathioprine; cholestyramine; antiviral medicine--acyclovir, ganciclovir, valacyclovir, valganciclovir; an antibiotic--amoxicillin, ciprofloxacin, metronidazole, norfloxacin, rifampin, sulfa drugs; or a stomach acid reducer--esomeprazole, lansoprazole, omeprazole, Nexium, Prevacid, Prilosec, Protonix, and others. This list is not complete and many other drugs may affect mycophenolate mofetil. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is mycophenolic acid? Mycophenolic acid is used with other medicines to prevent organ rejection after a kidney transplant. mycophenolic acid is for use in adults and children at least 5 years old. Mycophenolic acid may also be used for purposes not listed in this medication guide. Warnings This medicine can cause a miscarriage or birth defects when used during pregnancy. Both men and women should use effective birth control to prevent pregnancy during and shortly after treatment with mycophenolic acid. Using mycophenolic acid may increase your risk of cancer, serious infections, or kidney transplant failure. Call your doctor right away if you have symptoms such as: fever, swollen glands, weight loss, vomiting or diarrhea, painful urination, a new skin lesion, any change in your mental state, weakness on one side of your body, or pain near your transplanted kidney. Before taking this medicine You should not use mycophenolic acid if you are allergic to mycophenolic acid, mycophenolate mofetil, or mycophenolate sodium. Talk with your doctor about the risks and benefits of mycophenolic acid. This medicine can affect your immune system, which may increase your risk of cancer, serious or fatal infections, or kidney transplant failure. Tell your doctor if you have ever had: a stomach ulcer or problems with digestion; hepatitis B or C or other a viral infection (may become active or get worse while you are using mycophenolic acid); or a rare inherited enzyme deficiency such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome. This medicine can cause a miscarriage or birth defects, especially during the first 3 months of pregnancy. You will need to have a negative pregnancy test before and during treatment with this medicine. If you are able to get pregnant, you must use specific forms of birth control to prevent pregnancy while using mycophenolic acid, and for at least 6 weeks after your last dose. Sexually active men and their partners should use effective contraception during treatment and for at least 90 days after the last dose. Mycophenolic acid can make birth control pills less effective. Ask your doctor about using an additional barrier form of birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy. You do not need to use additional birth control if you use an intrauterine device (IUD), if you have had a tubal ligation, or if your sexual partner has had a vasectomy. This medicine comes with patient instructions about the most effective non-hormonal forms of birth control to use. Follow these directions carefully. Ask your doctor if you have any questions. If a pregnancy occurs during treatment, do not stop taking mycophenolic acid. Call your doctor for instructions. Also call the Mycophenolate Pregnancy Registry (1-800-617-8191). Mycophenolic acid is sometimes given to pregnant women. Your doctor will decide whether you should use this medicine if you are unable to use other needed transplant medications. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. How should I take mycophenolic acid? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow the tablet whole and do not crush, chew, or break it. Mycophenolic acid (Myfortic) and mycophenolate mofetil (CellCept) are not absorbed equally in the body. Avoid medication errors by using only the brand, form, and strength of this medicine that your doctor has prescribed. You will need frequent medical tests. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking mycophenolic acid? Avoid taking an antacid together with mycophenolic acid. Mycophenolic acid can make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Do not receive a "live" vaccine while using mycophenolic acid. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles). Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection. You must not donate blood or sperm while using mycophenolic acid, and for at least 6 weeks (for blood) or 90 days (for sperm) after your last dose. Mycophenolic acid side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Mycophenolic acid may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly. Mycophenolic acid affects your immune system and may increase your risk of cancer or serious infection. Call your doctor right away if you have: fever of 100.5 degrees F or higher, swollen glands, painful mouth sores, cold or flu symptoms, headache, ear pain; stomach pain, vomiting, diarrhea, weight loss; weakness on one side of your body, loss of muscle control; confusion, thinking problems, loss of interest in things that normally interest you; pain or burning when you urinate; dark urine, jaundice (yellowing of the skin or eyes); pain or tenderness around the transplanted kidney; tingly or painful blistering rash on one side of your body; swelling, warmth, redness, or oozing around a skin wound; or a new skin lesion, or a mole that has changed in size or color. Also call your doctor at once if you have: bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or low blood cell counts--fever, chills, tiredness, flu-like symptoms, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath. Common side effects may include: upset stomach, nausea, vomiting; diarrhea, constipation; low blood cell counts, infections; sleep problems (insomnia); painful urination; or pain after surgery. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Mycophenolic acid dosing information Usual Adult Dose for Organ Transplant -- Rejection Prophylaxis: 720 mg orally 2 times daily Comments: -This drug should be used in combination with cyclosporine and corticosteroids. -Take on an empty stomach 1 hour before or 2 hours after food. -Swallow tablets whole; do not crush, chew, or divide. Use: For prophylaxis of organ rejection in kidney transplant Usual Pediatric Dose for Organ Transplant -- Rejection Prophylaxis: 5 years and older: -In conversion (at least 6 months posttransplant): 400 mg/m2 orally 2 times a day (up to a maximum dose of 720 mg 2 times a day) Note: Pediatric patients with a BSA of 1.19 to 1.58 m2 may be dosed either with three of the 180 mg tablets, or one 180 mg tablet plus one 360 mg tablet 2 times a day. Patients with a BSA greater than 1.58 m2 may be dosed either with four of the 180 mg tablets, or two of the 360 mg tablets twice daily. Pediatric doses for patients with BSA less than 1.19 m2 cannot be accurately administered using currently available formulations of this drug. Comments: -This drug should be used in combination with cyclosporine and corticosteroids. -Take on an empty stomach 1 hour before or 2 hours after food. -Swallow tablets whole; do not crush, chew, or divide. Use: For the prophylaxis of organ rejection in pediatric patients 5 years of age and older who are at least 6 months post kidney transplant   What other drugs will affect mycophenolic acid? Tell your doctor about all your other medicines, especially: azathioprine; cholestyramine; or antiviral medicine--acyclovir, ganciclovir. This list is not complete. Other drugs may affect mycophenolic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is nabumetone? Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID). Nabumetone works by reducing hormones that cause inflammation and pain in the body. Nabumetone is used to relieve the symptoms of rheumatoid arthritis or osteoarthritis. Nabumetone may also be used for purposes not listed in this medication guide. Warnings Nabumetone can increase your risk of fatal heart attack or stroke. Do not use nabumetone just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Nabumetone may also cause stomach or intestinal bleeding, which can be fatal. Before taking this medicine Nabumetone can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Nabumetone may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using nabumetone, especially in older adults. You should not use nabumetone if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Tell your doctor if you have ever had: heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke; a heart attack, stroke, or blood clot; stomach ulcers or bleeding; asthma; liver or kidney disease; or fluid retention. If you are pregnant, you should not take nabumetone unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. You should not breastfeed while using this medicine. Nabumetone is not approved for use by anyone younger than 18 years old. How should I take nabumetone? Follow all directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Use the lowest dose that is effective in treating your condition. You may take nabumetone with or without food. If you use nabumetone long-term, you may need frequent medical tests. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking nabumetone? Avoid drinking alcohol. It may increase your risk of stomach bleeding. Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to nabumetone (such as aspirin, ibuprofen, ketoprofen, or naproxen). Nabumetone could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Nabumetone side effects Get emergency medical help if you have signs of an allergic reaction (hives, sneezing, runny or stuffy nose, wheezing, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath. Stop using nabumetone and call your doctor at once if you have: shortness of breath (even with mild exertion); swelling or rapid weight gain; the first sign of any skin rash, no matter how mild; signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; liver problems--nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); kidney problems--little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet. Common side effects may include: stomach pain, indigestion, nausea; diarrhea, constipation, gas; swelling in your hands and feet; headache, dizziness; itching, skin rash; or ringing in your ears. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Nabumetone dosing information Usual Adult Dose for Osteoarthritis: Initial dose: 1000 mg orally once a day Maintenance dose: 1500 to 2000 mg orally per day in 1 or 2 divided doses Maximum dose: 2000 mg/day Comments: -Patients weighing less than 50 kg may be less likely to require dosages beyond 1000 mg. -Once response to therapy is determined, dose and frequency should be adjusted to the lowest effective dose for the shortest duration possible to suit the individual patient's treatment goals. Use: For the relief of signs and symptoms of osteoarthritis and rheumatoid arthritis. Usual Adult Dose for Rheumatoid Arthritis: Initial dose: 1000 mg orally once a day Maintenance dose: 1500 to 2000 mg orally per day in 1 or 2 divided doses Maximum dose: 2000 mg/day Comments: -Patients weighing less than 50 kg may be less likely to require dosages beyond 1000 mg. -Once response to therapy is determined, dose and frequency should be adjusted to the lowest effective dose for the shortest duration possible to suit the individual patient's treatment goals. Use: For the relief of signs and symptoms of osteoarthritis and rheumatoid arthritis.   What other drugs will affect nabumetone? Ask your doctor before using nabumetone if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily. Tell your doctor about all your other medicines, especially: lithium; methotrexate; a blood thinner (warfarin, Coumadin, Jantoven); heart or blood pressure medication, including a diuretic or "water pill"; or steroid medicine (such as prednisone). This list is not complete. Other drugs may affect nabumetone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is naltrexone? Naltrexone blocks the effects of opioid medication, including pain relief or feelings of well-being that can lead to opioid abuse. An opioid is sometimes called a narcotic. Vivitrol is used as part of a treatment program for drug or alcohol dependence. Naltrexone injection is used to prevent relapse in adults who became dependent on opioid medicine and then stopped using it. Naltrexone can help keep you from feeling a "need" to use the opioid. Naltrexone injection is also used to treat alcoholism by reducing your urge to drink alcohol. This may help you drink less or stop drinking altogether. You should not be drinking at the time you receive your first injection. Naltrexone is not a permanent cure for drug addiction or alcoholism. Warnings You should be treated with naltrexone only if you have not recently used: any opioid medicine, buprenorphine, methadone, or medicine to treat a cold, cough, diarrhea, or pain. Using these medicines in the 7 to 14 days before starting naltrexone can cause sudden opioid withdrawal symptoms. Do not use opioid medication, heroin, or other street drugs while you are receiving this medicine. Doing so could result in dangerous effects, including coma and death. Call your doctor if you have ongoing or worsening pain, redness, itching, bruising, swelling, or a hard lump where the medicine was injected. Naltrexone can harm your liver. Tell your doctor if you have upper stomach pain, dark urine, or yellowing in the whites of your eyes. After receiving naltrexone, your body will be more sensitive to opioids if you use an opioid medicine in the future. Using the same amount you used before could lead to overdose or death. Before taking this medicine You should not receive a naltrexone injection if you still use opioid medicine, or you could have sudden and severe withdrawal symptoms. You should not be treated with naltrexone if you are allergic to it, or if: you are currently addicted to opioids; you are having withdrawal symptoms from opioid addiction; you have used any opioid medicine within the past 7 to 14 days (including fentanyl, Vicodin, OxyContin, and many others); you have used methadone or buprenorphine (Subutex, Butrans, Suboxone, Zubsolv) in the past 14 days; or you have used any medicine to treat a cold, cough, diarrhea, or pain in the past 7 to 14 days. To make sure naltrexone is safe for you, tell your doctor if you have ever had: liver disease; kidney disease; or bleeding problems such as hemophilia. Tell your doctor if you are pregnant or breastfeeding. It is not known whether naltrexone will harm an unborn baby. However, if you use opioid medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks. How is naltrexone given? Naltrexone is injected into a muscle. This injection is usually given once a month (every 4 weeks) and can be given only by a healthcare professional. Get your naltrexone injection regularly to get the most benefit. You may notice pain, redness, itching, bruising, swelling, or a hard lump where the medicine was injected. Call your doctor if you have this type of reaction, especially if it gets worse or does not clear up within 2 weeks. Naltrexone injections are only part of a complete treatment program that may also include additional forms of counseling and/or monitoring. Follow your doctor's instructions very closely. In case of emergency, wear or carry medical identification to let others know you are using this medicine. After using naltrexone, your body will be more sensitive to opioids. If you use an opioid medicine in the future, you will need to use less than before naltrexone treatment. Using the same amount you used before could lead to overdose or death. Dosing information Usual Adult Dose for Alcohol Dependence: Injection: 380 mg intramuscularly every 4 weeks/once a month Usual Adult Dose for Opiate Addiction: Injection: 380 mg intramuscularly every 4 weeks/once a month Comments: -There is no data specifically addressing switching from buprenorphine or methadone to naltrexone, however some patients have reported severe manifestations of precipitated withdrawal when switched from an opioid agonist to opioid antagonist therapy. -Patients switching from buprenorphine or methadone may be vulnerable to precipitated withdrawal for up to 2 weeks. -Be prepared to manage withdrawal symptomatically with non-opioid medications. -This drug is of value only as a part of a comprehensive management plan that includes measures to ensure the patient takes this medication. Use(s): Blockade of the effects of exogenously administered opioids   What happens if I miss a dose? Call your doctor for instructions if you miss an appointment for your injection. What happens if I overdose? Since this injection is given by a healthcare professional in a medical setting, an overdose is unlikely to occur. However, overdose symptoms may include nausea, stomach pain, drowsiness, dizziness, or a reaction where an injection was given (such as severe pain or skin changes). What should I avoid while using naltrexone? Do not use opioid medication, heroin, or other street drugs while you are receiving naltrexone. Once naltrexone is injected, it cannot be removed from your body. Never try to overcome the effects of naltrexone by taking large doses of opioids. Doing so could result in dangerous effects, including coma and death. Ask your doctor before using any medicine to treat a cold, cough, diarrhea, or pain. These medicines may contain opioids and may not work as well while you are using this medicine. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Naltrexone side effects Get emergency medical help if you have signs of an allergic reaction to naltrexone: hives; chest pain, wheezing, difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat. Using opioid medicine while you are receiving this medicine could stimulate opioid withdrawal symptoms. Common withdrawal symptoms are yawning, sweating, fever, stomach pain, vomiting, diarrhea, watery eyes, runny nose, goose bumps, body aches, shaking, muscle twitching, trouble sleeping, and feeling restless or anxious. Call your doctor at once if you have: weak or shallow breathing; new or worsening cough, wheezing, trouble breathing; severe pain, swelling, blistering, skin changes, a dark scab, or a hard lump where the medicine was injected; liver problems - stomach pain (upper right side), dark urine, tiredness, jaundice (yellowing of the skin or eyes); or symptoms of depression - unusual mood or behavior changes, loss of interest in things you once enjoyed, crying, new sleep problems, thoughts about hurting yourself. You may feel nauseated the first time you receive this medicine. You may also have a headache, tiredness, joint and muscle pain, loss of appetite, and vomiting. Common naltrexone side effects may include: nausea, vomiting, loss of appetite; joint pain, muscle cramps; dizziness, drowsiness; sleep problems (insomnia); tooth pain; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect naltrexone? Other drugs may interact with naltrexone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is naproxen? Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Naproxen is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps. It can also be used to treat acute pain caused by other conditions not listed in this medication guide. The delayed-release or extended-release tablets are slower-acting forms of naproxen that are used only for treating chronic conditions such as arthritis or ankylosing spondylitis. These forms will not work fast enough to treat acute pain. Warnings You should not use naproxen if you have a history of allergic reaction to aspirin or other NSAID (nonsteroidal anti-inflammatory drug). Naproxen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Get emergency medical help if you have swelling of the face or throat, chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance. Stop taking naproxen and notify your physician if you notice stomach pain, tiredness or weakness, yellow skin or eyes, nausea, vomiting, bloody or black and sticky bowel movements, skin rash, unexplained weight loss or weight gain, or swelling of the hands and feet. Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. Before taking this medicine Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. You should not use naproxen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Ask a doctor before giving naproxen to a child younger than 12 years old. Ask a doctor or pharmacist if it is safe for you to use this medicine if you have: heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke; a history of heart attack, stroke, or blood clot; a history of stomach ulcers or bleeding; asthma; liver or kidney disease; fluid retention: or if you take aspirin to prevent heart attack or stroke. If you are pregnant, you should not take naproxen unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. It may not be safe to breastfeed while using naproxen. Ask your doctor about any risk. Naproxen is not approved for use by anyone younger than 2 years old. Do not give this medicine to a child without medical advice. How should I take naproxen? Use naproxen exactly as directed on the label, or as prescribed by your doctor. Do not take this medicine in larger amounts or for longer than recommended. Use the lowest dose that is effective in treating your condition. Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. If you change brands, strengths, or forms of this medicine, your dosage needs may change. Ask your pharmacist if you have any questions about the kind of naproxen you are using. If a child is using this medicine, tell your doctor if the child has any changes in weight. Doses are based on weight in children, and any changes may affect your child's dose. If you use this medicine long-term, you may need frequent medical tests. This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using naproxen. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.   What happens if I miss a dose? Since naproxen is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid drinking alcohol. It may increase your risk of stomach bleeding. Avoid taking aspirin unless your doctor tells you to. Ask your doctor before taking any other medication for pain, arthritis, fever, or swelling. Many medicines available over the counter contain aspirin, salicylates, or other medicines similar to naproxen (such as ibuprofen or ketoprofen). Taking certain products together can cause you to get too much of this type of medication. Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for your body to absorb naproxen. Naproxen side effects Get emergency medical help if you have signs of an allergic reaction to naproxen: wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat. Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath. Stop using naproxen and call your doctor at once if you have: shortness of breath (even with mild exertion); swelling or rapid weight gain; the first sign of any skin rash, no matter how mild; signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; liver problems - nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); kidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; low red blood cells (anemia) - pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Common naproxen side effects may include: indigestion, heartburn, stomach pain, nausea; headache, dizziness, drowsiness; bruising, itching, rash; swelling; or ringing in your ears. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect naproxen? Ask your doctor before using naproxen if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may cause you to bruise or bleed easily. Ask a doctor or pharmacist if it is safe for you to use this medicine if you are also using any of the following drugs: cholestyramine; cyclosporine; digoxin; lithium; methotrexate; pemetrexed; phenytoin or similar seizure medications; probenecid; warfarin (Coumadin, Jantoven) or similar blood thinners; a diuretic or "water pill"; heart or blood pressure medication; or insulin or oral diabetes medicine. This list is not complete. Other drugs may interact with naproxen, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is naproxen? Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Naproxen is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps. It can also be used to treat acute pain caused by other conditions not listed in this medication guide. The delayed-release or extended-release tablets are slower-acting forms of naproxen that are used only for treating chronic conditions such as arthritis or ankylosing spondylitis. These forms will not work fast enough to treat acute pain. Warnings You should not use naproxen if you have a history of allergic reaction to aspirin or other NSAID (nonsteroidal anti-inflammatory drug). Naproxen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Get emergency medical help if you have swelling of the face or throat, chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance. Stop taking naproxen and notify your physician if you notice stomach pain, tiredness or weakness, yellow skin or eyes, nausea, vomiting, bloody or black and sticky bowel movements, skin rash, unexplained weight loss or weight gain, or swelling of the hands and feet. Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. Before taking this medicine Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. You should not use naproxen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Ask a doctor before giving naproxen to a child younger than 12 years old. Ask a doctor or pharmacist if it is safe for you to use this medicine if you have: heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke; a history of heart attack, stroke, or blood clot; a history of stomach ulcers or bleeding; asthma; liver or kidney disease; fluid retention: or if you take aspirin to prevent heart attack or stroke. If you are pregnant, you should not take naproxen unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. It may not be safe to breastfeed while using naproxen. Ask your doctor about any risk. Naproxen is not approved for use by anyone younger than 2 years old. Do not give this medicine to a child without medical advice. How should I take naproxen? Use naproxen exactly as directed on the label, or as prescribed by your doctor. Do not take this medicine in larger amounts or for longer than recommended. Use the lowest dose that is effective in treating your condition. Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. If you change brands, strengths, or forms of this medicine, your dosage needs may change. Ask your pharmacist if you have any questions about the kind of naproxen you are using. If a child is using this medicine, tell your doctor if the child has any changes in weight. Doses are based on weight in children, and any changes may affect your child's dose. If you use this medicine long-term, you may need frequent medical tests. This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using naproxen. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.   What happens if I miss a dose? Since naproxen is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid drinking alcohol. It may increase your risk of stomach bleeding. Avoid taking aspirin unless your doctor tells you to. Ask your doctor before taking any other medication for pain, arthritis, fever, or swelling. Many medicines available over the counter contain aspirin, salicylates, or other medicines similar to naproxen (such as ibuprofen or ketoprofen). Taking certain products together can cause you to get too much of this type of medication. Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for your body to absorb naproxen. Naproxen side effects Get emergency medical help if you have signs of an allergic reaction to naproxen: wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat. Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath. Stop using naproxen and call your doctor at once if you have: shortness of breath (even with mild exertion); swelling or rapid weight gain; the first sign of any skin rash, no matter how mild; signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; liver problems - nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); kidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; low red blood cells (anemia) - pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Common naproxen side effects may include: indigestion, heartburn, stomach pain, nausea; headache, dizziness, drowsiness; bruising, itching, rash; swelling; or ringing in your ears. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect naproxen? Ask your doctor before using naproxen if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may cause you to bruise or bleed easily. Ask a doctor or pharmacist if it is safe for you to use this medicine if you are also using any of the following drugs: cholestyramine; cyclosporine; digoxin; lithium; methotrexate; pemetrexed; phenytoin or similar seizure medications; probenecid; warfarin (Coumadin, Jantoven) or similar blood thinners; a diuretic or "water pill"; heart or blood pressure medication; or insulin or oral diabetes medicine. This list is not complete. Other drugs may interact with naproxen, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is nebivolol? Nebivolol is a beta-blocker that is used to treat hypertension (high blood pressure). Lowering blood pressure may lower your risk of a stroke or heart attack. Nebivolol may also be used for purposes not listed in this medication guide. Warnings Do not skip doses or stop taking nebivolol without first talking to your doctor. Before taking this medicine You should not take nebivolol if you are allergic to it, or if you have: a serious heart condition such as heart failure, "AV block" (2nd or 3rd degree), or sick sinus syndrome (unless you have a pacemaker); very slow heartbeats; severe liver disease; or if your heart cannot pump blood properly. Tell your doctor if you have ever had: asthma, bronchitis, emphysema; a heart attack; problems with circulation (especially in your feet and legs); diabetes (taking nebivolol can make it harder for you to tell when you have low blood sugar); a thyroid disorder; liver or kidney disease; allergies; or pheochromocytoma (tumor of the adrenal gland). Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether nebivolol will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby. You should not breastfeed while using nebivolol. How should I take nebivolol? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take nebivolol with or without food. Your blood pressure will need to be checked often. If you need surgery, tell the surgeon ahead of time that you are using nebivolol. You should not skip doses or stop using nebivolol suddenly. Stopping suddenly may make your condition worse or cause serious heart problems, including heart attack. Follow your doctor's instructions about tapering your dose. Keep using nebivolol as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include slow heart rate, dizziness, vomiting, trouble breathing, or feeling like you might pass out. What should I avoid while taking nebivolol? Avoid driving or hazardous activity until you know how nebivolol will affect you. Your reactions could be impaired. Nebivolol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; rapid weight gain; shortness of breath; slow or uneven heartbeats; or numbness or cold feeling in your hands and feet. Common side effects may include: dizziness; swelling in your legs; slow heartbeats; tiredness; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Nebivolol dosing information Usual Adult Dose for Hypertension: Initial dose: 5 mg orally once a day Dose adjustment: Titrate dose at 2-week intervals up to 40 mg once a day as needed. Maximum dose: 40 mg per day Comments: -Titrating doses more frequently than every 2 weeks is unlikely to be beneficial. -The dose should be individualized to patient requirements. Use: For the management of hypertension, alone or with another antihypertensive agent.   What other drugs will affect nebivolol? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Many drugs can affect nebivolol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is niacin? Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. It is also present in many multiple vitamins and nutritional supplements. Niacin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides, and increase levels of "good" cholesterol (high-density lipoprotein, or HDL). Niacin may also be used for purposes not listed in this medication guide. Warnings You should not take niacin if you have severe liver disease, a stomach ulcer, or active bleeding. Niacin can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin). These effects can be made worse if you drink alcohol or hot beverages shortly after you take this medicine. These effects should disappear over time as you keep taking the medication. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Avoid taking colestipol (Colestid) or cholestyramine (Locholest, Prevalite, Questran) at the same time you take niacin. If you take either of these other medications, take them at least 4 to 6 hours before or after you take this medicine. Niacin is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely. Before taking this medicine You should not take niacin if you are allergic to it. To make sure you can safely take niacin, tell your doctor if you have ever had: severe liver disease; a stomach ulcer; or active bleeding. Tell your doctor if you have ever had: liver disease; heart disease, chest pain (angina); gout; or diabetes. It is not known whether niacin will harm an unborn baby. You may not be able to use this medicine during pregnancy. Tell your doctor right away if you become pregnant. You should not breastfeed while using this medicine. Niacin is not approved for use by anyone younger than 18 years old. How should I take niacin ? Use niacin exactly as directed on the label, or as prescribed by your doctor. Read all medication guides or instruction sheets. Niacin can cause flushing (warmth, itching, redness, or tingly feeling under your skin). These effects should disappear over time as you keep taking the medicine. Flushing may be worse if you drink alcohol or hot beverages shortly after taking niacin. Swallow the capsule or tablet whole and do not crush, chew, break, or open it. Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes. If you stop taking niacin for any length of time, talk with your doctor before starting the medication again. You may need to restart the medication at a lower dose. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine. Niacin is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Your doctor may recommend you take aspirin or an NSAID (such as ibuprofen, Advil, or Aleve) to help prevent flushing. Keep using these medicines for as long as your doctor has prescribed. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid drinking alcohol. It may increase your risk of liver damage, and can also worsen the flushing effects of niacin. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid eating foods high in fat or cholesterol, or niacin will not be as effective. Niacin side effects Get emergency medical help if you have signs of an allergic reaction to niacin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; irregular heartbeats; severe warmth or redness under your skin; vision problems; or jaundice (yellowing of the skin or eyes). Common niacin side effects may include: flushing (sudden warmth, redness, or tingly feeling); upset stomach, vomiting, diarrhea; abnormal liver function tests; itching, dry skin; cough; skin discoloration; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect niacin? Tell your doctor about all your other medicines, especially: statin cholesterol medication; heart or blood pressure medication; or other medicines that lower blood pressure. This list is not complete. Other drugs may interact with niacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is niacin? Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. It is also present in many multiple vitamins and nutritional supplements. Niacin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides, and increase levels of "good" cholesterol (high-density lipoprotein, or HDL). Niacin may also be used for purposes not listed in this medication guide. Warnings You should not take niacin if you have severe liver disease, a stomach ulcer, or active bleeding. Niacin can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin). These effects can be made worse if you drink alcohol or hot beverages shortly after you take this medicine. These effects should disappear over time as you keep taking the medication. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Avoid taking colestipol (Colestid) or cholestyramine (Locholest, Prevalite, Questran) at the same time you take niacin. If you take either of these other medications, take them at least 4 to 6 hours before or after you take this medicine. Niacin is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely. Before taking this medicine You should not take niacin if you are allergic to it. To make sure you can safely take niacin, tell your doctor if you have ever had: severe liver disease; a stomach ulcer; or active bleeding. Tell your doctor if you have ever had: liver disease; heart disease, chest pain (angina); gout; or diabetes. It is not known whether niacin will harm an unborn baby. You may not be able to use this medicine during pregnancy. Tell your doctor right away if you become pregnant. You should not breastfeed while using this medicine. Niacin is not approved for use by anyone younger than 18 years old. How should I take niacin ? Use niacin exactly as directed on the label, or as prescribed by your doctor. Read all medication guides or instruction sheets. Niacin can cause flushing (warmth, itching, redness, or tingly feeling under your skin). These effects should disappear over time as you keep taking the medicine. Flushing may be worse if you drink alcohol or hot beverages shortly after taking niacin. Swallow the capsule or tablet whole and do not crush, chew, break, or open it. Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes. If you stop taking niacin for any length of time, talk with your doctor before starting the medication again. You may need to restart the medication at a lower dose. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine. Niacin is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Your doctor may recommend you take aspirin or an NSAID (such as ibuprofen, Advil, or Aleve) to help prevent flushing. Keep using these medicines for as long as your doctor has prescribed. Store at room temperature away from moisture and heat. Detailed Niacin dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid drinking alcohol. It may increase your risk of liver damage, and can also worsen the flushing effects of niacin. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid eating foods high in fat or cholesterol, or niacin will not be as effective. Niacin side effects Get emergency medical help if you have signs of an allergic reaction to niacin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; irregular heartbeats; severe warmth or redness under your skin; vision problems; or jaundice (yellowing of the skin or eyes). Common niacin side effects may include: flushing (sudden warmth, redness, or tingly feeling); upset stomach, vomiting, diarrhea; abnormal liver function tests; itching, dry skin; cough; skin discoloration; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Niacin side effects (more detail) What other drugs will affect niacin? Tell your doctor about all your other medicines, especially: statin cholesterol medication; heart or blood pressure medication; or other medicines that lower blood pressure. This list is not complete. Other drugs may interact with niacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is niacin? Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. It is also present in many multiple vitamins and nutritional supplements. Niacin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides, and increase levels of "good" cholesterol (high-density lipoprotein, or HDL). Niacin may also be used for purposes not listed in this medication guide. Warnings You should not take niacin if you have severe liver disease, a stomach ulcer, or active bleeding. Niacin can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin). These effects can be made worse if you drink alcohol or hot beverages shortly after you take this medicine. These effects should disappear over time as you keep taking the medication. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Avoid taking colestipol (Colestid) or cholestyramine (Locholest, Prevalite, Questran) at the same time you take niacin. If you take either of these other medications, take them at least 4 to 6 hours before or after you take this medicine. Niacin is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely. Before taking this medicine You should not take niacin if you are allergic to it. To make sure you can safely take niacin, tell your doctor if you have ever had: severe liver disease; a stomach ulcer; or active bleeding. Tell your doctor if you have ever had: liver disease; heart disease, chest pain (angina); gout; or diabetes. It is not known whether niacin will harm an unborn baby. You may not be able to use this medicine during pregnancy. Tell your doctor right away if you become pregnant. You should not breastfeed while using this medicine. Niacin is not approved for use by anyone younger than 18 years old. How should I take niacin ? Use niacin exactly as directed on the label, or as prescribed by your doctor. Read all medication guides or instruction sheets. Niacin can cause flushing (warmth, itching, redness, or tingly feeling under your skin). These effects should disappear over time as you keep taking the medicine. Flushing may be worse if you drink alcohol or hot beverages shortly after taking niacin. Swallow the capsule or tablet whole and do not crush, chew, break, or open it. Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes. If you stop taking niacin for any length of time, talk with your doctor before starting the medication again. You may need to restart the medication at a lower dose. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine. Niacin is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Your doctor may recommend you take aspirin or an NSAID (such as ibuprofen, Advil, or Aleve) to help prevent flushing. Keep using these medicines for as long as your doctor has prescribed. Store at room temperature away from moisture and heat. Detailed Niacin dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid drinking alcohol. It may increase your risk of liver damage, and can also worsen the flushing effects of niacin. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid eating foods high in fat or cholesterol, or niacin will not be as effective. Niacin side effects Get emergency medical help if you have signs of an allergic reaction to niacin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; irregular heartbeats; severe warmth or redness under your skin; vision problems; or jaundice (yellowing of the skin or eyes). Common niacin side effects may include: flushing (sudden warmth, redness, or tingly feeling); upset stomach, vomiting, diarrhea; abnormal liver function tests; itching, dry skin; cough; skin discoloration; or headache.  

What is nifedipine? Nifedipine is in a group of drugs called calcium channel blockers. It works by relaxing the muscles of your heart and blood vessels. Nifedipine is used to treat hypertension (high blood pressure) and angina (chest pain). Nifedipine may also be used for purposes not listed in this medication guide. What is the most important information I should know about nifedipine? You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. Before taking nifedipine, tell your doctor if you have kidney or liver disease, a blockage in your digestive tract (stomach or intestines), a history of stomach surgery, coronary artery disease, underactive thyroid, diabetes, or congestive heart failure. If you need surgery, tell the surgeon ahead of time that you are using nifedipine. You may need to stop using the medicine for a short time. Do not stop taking nifedipine without first talking to your doctor, even if you feel fine. Stopping suddenly may make your condition worse. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Before taking this medicine You should not use this medicine if you are allergic to nifedipine, if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. To make sure nifedipine is safe for you, tell your doctor if you have: severe COPD (chronic obstructive pulmonary disease); kidney disease; congestive heart failure; or if you take other medications, especially an antibiotic or antifungal medicine, an antidepressant, heart or blood pressure medicine, or drugs to treat HIV/AIDS or hepatitis C. It is not known whether nifedipine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Nifedipine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. The nifedipine extended-release tablet may contain lactose. Talk to your doctor before using this form of nifedipine if you have galactose intolerance, or severe problems with lactose (milk sugar). How should I take nifedipine? Take nifedipine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. You may need to take an extended-release tablet on an empty stomach. Follow the directions on your medicine label about taking this medication with or without food. Do not crush, chew, or break a nifedipine extended-release tablet. Swallow it whole. Your blood pressure will need to be checked often and you may need other blood tests at your doctor's office. Some tablet forms of nifedipine are made with a shell that is not absorbed or melted in the body. Part of the tablet shell may appear in your stool. This is a normal side effect of nifedipine and will not make the medication less effective. If you need surgery, tell the surgeon ahead of time that you are using nifedipine. You may need to stop using the medicine at least 36 hours before surgery. You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. If you are also taking a beta-blocker (atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others) you should not stop using the beta-blocker suddenly or you could have serious heart problems that will not be prevented by nifedipine. Follow your doctor's instructions about tapering your beta-blocker dose. You should not stop using nifedipine suddenly. Stopping suddenly may make your condition worse. If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid? Grapefruit and grapefruit juice may interact with nifedipine and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Nifedipine side effects Get emergency medical help if you have any signs of an allergic reaction to nifedipine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening angina; a light-headed feeling, like you might pass out; pounding heartbeats or fluttering in your chest; chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling; swelling in your ankles or feet; or upper stomach pain, jaundice (yellowing of the skin or eyes). Common nifedipine side effects may include: mild dizziness; flushing (warmth, redness, or tingly feeling); weakness, headache, mood changes; heartburn, nausea; tremors, muscle cramps; or cough, wheezing, sore throat, stuffy nose. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect nifedipine? Other drugs may interact with nifedipine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What is nifedipine? Nifedipine is in a group of drugs called calcium channel blockers. It works by relaxing the muscles of your heart and blood vessels. Nifedipine is used to treat hypertension (high blood pressure) and angina (chest pain). Nifedipine may also be used for purposes not listed in this medication guide. What is the most important information I should know about nifedipine? You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. Before taking nifedipine, tell your doctor if you have kidney or liver disease, a blockage in your digestive tract (stomach or intestines), a history of stomach surgery, coronary artery disease, underactive thyroid, diabetes, or congestive heart failure. If you need surgery, tell the surgeon ahead of time that you are using nifedipine. You may need to stop using the medicine for a short time. Do not stop taking nifedipine without first talking to your doctor, even if you feel fine. Stopping suddenly may make your condition worse. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Before taking this medicine You should not use this medicine if you are allergic to nifedipine, if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. To make sure nifedipine is safe for you, tell your doctor if you have: severe COPD (chronic obstructive pulmonary disease); kidney disease; congestive heart failure; or if you take other medications, especially an antibiotic or antifungal medicine, an antidepressant, heart or blood pressure medicine, or drugs to treat HIV/AIDS or hepatitis C. It is not known whether nifedipine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Nifedipine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. The nifedipine extended-release tablet may contain lactose. Talk to your doctor before using this form of nifedipine if you have galactose intolerance, or severe problems with lactose (milk sugar). How should I take nifedipine? Take nifedipine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. You may need to take an extended-release tablet on an empty stomach. Follow the directions on your medicine label about taking this medication with or without food. Do not crush, chew, or break a nifedipine extended-release tablet. Swallow it whole. Your blood pressure will need to be checked often and you may need other blood tests at your doctor's office. Some tablet forms of nifedipine are made with a shell that is not absorbed or melted in the body. Part of the tablet shell may appear in your stool. This is a normal side effect of nifedipine and will not make the medication less effective. If you need surgery, tell the surgeon ahead of time that you are using nifedipine. You may need to stop using the medicine at least 36 hours before surgery. You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. If you are also taking a beta-blocker (atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others) you should not stop using the beta-blocker suddenly or you could have serious heart problems that will not be prevented by nifedipine. Follow your doctor's instructions about tapering your beta-blocker dose. You should not stop using nifedipine suddenly. Stopping suddenly may make your condition worse. If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid? Grapefruit and grapefruit juice may interact with nifedipine and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Nifedipine side effects Get emergency medical help if you have any signs of an allergic reaction to nifedipine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening angina; a light-headed feeling, like you might pass out; pounding heartbeats or fluttering in your chest; chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling; swelling in your ankles or feet; or upper stomach pain, jaundice (yellowing of the skin or eyes). Common nifedipine side effects may include: mild dizziness; flushing (warmth, redness, or tingly feeling); weakness, headache, mood changes; heartburn, nausea; tremors, muscle cramps; or cough, wheezing, sore throat, stuffy nose. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect nifedipine? Other drugs may interact with nifedipine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What is Nilandron? Nilandron is used to treat prostate cancer that has spread to other parts of the body. Nilandron is for use in men who have undergone surgical castration. Nilandron may also be used for purposes not listed in this medication guide. Warnings You should not use Nilandron if you have severe liver disease or severe breathing problems. Nilandron can cause serious lung problems. Call your doctor right away if you have chest pain, wheezing, dry cough, fever, and new or worsening shortness of breath. Before taking this medicine You should not use Nilandron if you are allergic to it, or if you have: severe liver disease; or severe breathing problems. Tell your doctor if you have ever had: liver disease; or asthma or another lung disease. Nilandron is not for use in women, and the effects of Nilandron during pregnancy or in breastfeeding women are unknown. How should I take Nilandron? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Treatment with Nilandron should be started on the day of or on the day after surgical castration. You may take Nilandron with or without food. Do not stop taking this medication without first talking to your doctor. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking Nilandron? Nilandron may cause a delay in your ability to see in the dark after you have been in a lighted area. Be careful when driving at night, when entering a tunnel, and in similar situations. Wearing tinted glasses may help lessen this effect. Drinking alcohol with Nilandron may cause dizziness, flushing (warmth, redness, or tingly feeling), or other unpleasant symptoms. Nilandron side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: chest pain, wheezing, dry cough, fever; new or worsening shortness of breath; flu symptoms, pale skin, feeling tired; or liver problems--nausea, vomiting, loss of appetite, right-sided upper stomach pain, flu-like symptoms, dark urine, jaundice (yellowing of the skin or eyes). Common side effects may include: hot flashes; dizziness; constipation; nausea or vomiting, loss of appetite; skin rash; decreased libido, impotence; or vision changes. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect Nilandron? Other drugs may affect Nilandron, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Uses Nitroglycerin extended-release capsules are used to prevent chest pain (angina) in people with a certain heart condition (coronary artery disease). This medication belongs to a class of drugs known as nitrates. Angina occurs when the heart muscle is not getting enough blood. This drug works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. It is also not intended to be taken just before physical activities (such as exercise, sexual activity) to prevent chest pain. Other medications may be needed in these situations. Consult your doctor for more details. How to use Nitroglycerin Take this medication by mouth, usually 3 to 4 times daily or as directed by your doctor. It is important to take the drug at the same times each day. Do not change the dosing times unless directed by your doctor. The dosage is based on your medical condition and response to treatment. Swallow this medication whole. Do not crush or chew the capsules. Doing so can release all of the drug at once and may increase your risk of side effects. Use this medication regularly to get the most benefit from it. Do not suddenly stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Tell your doctor if this medication stops working well (for example, you have worsening chest pain or it occurs more often). Side Effects Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Headache is often a sign that this medication is working. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). If the headaches continue or become severe, tell your doctor promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, fast/irregular/pounding heartbeat. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088  

What is nitroglycerin rectal? Nitroglycerin rectal is used to treat moderate to severe pain caused by chronic anal fissures (tears in the skin lining your rectum). Nitroglycerin rectal may also be used for purposes not listed in this medication guide. Warnings You should not use nitroglycerin if you are also using medicine to treat pulmonary arterial hypertension or erectile dysfunction, or if you have severe anemia (a lack of red blood cells), or increased pressure inside your skull. Before taking this medicine You should not use nitroglycerin rectal if you are allergic to it, or if you have: severe anemia (a lack of red blood cells); increased pressure inside the skull; or if you also use erectile dysfunction medicine such as Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, or vardenafil. Do not use nitroglycerin rectal if you have early signs of a heart attack (chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling). Seek emergency medical attention if you have symptoms of a heart attack. Tell your doctor if you have ever had: congestive heart failure; heart attack; a blood vessel disorder; low blood pressure; or headaches. Tell your doctor if you are pregnant or breastfeeding. Nitroglycerin rectal is not approved for use by anyone younger than 18 years old. How should I use nitroglycerin rectal? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Do not take a rectal suppository or enema by mouth. Use it only in your rectum. Nitroglycerin rectal can cause severe headaches. Ask your doctor before using any headache pain medication. It may take up to 3 weeks before your symptoms improve. Keep using as directed and tell your doctor if your symptoms do not improve or if they get worse while using nitroglycerin rectal. Store at room temperature away from moisture and heat. Keep the tube tightly closed when not in use. Throw away any nitroglycerin rectal ointment you have not used within 8 weeks after you first opened the tube.   What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of nitroglycerin can be fatal. Overdose symptoms may include a severe throbbing headache, confusion, fever, fast or pounding heartbeats, dizziness, vision problems, vomiting, bloody diarrhea, trouble breathing, cold or clammy skin, fainting, and seizures. What should I avoid while using nitroglycerin rectal? Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Drinking alcohol can increase certain side effects such as dizziness, drowsiness, feeling light-headed, or fainting. Avoid getting nitroglycerin in your eyes, mouth, or vagina. Nitroglycerin rectal side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: pounding heartbeats or fluttering in your chest; slow heart rate; a light-headed feeling, like you might pass out; or heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. Nitroglycerin can cause severe headaches. These headaches may gradually become less severe as you continue to use nitroglycerin. Do not stop using this medicine. Ask your doctor before using any headache pain medication. Common side effects may include: headache; or dizziness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect nitroglycerin rectal? Tell your doctor about all your current medicines, especially: aspirin or heparin; medicine used to treat blood clots; blood pressure medication; ergot medicine--dihydroergotamine, ergotamine, ergonovine, methylergonovine. other nitroglycerin medication. This list is not complete and many other drugs may affect nitroglycerin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is norethindrone? Norethindrone is a form of progesterone, a female hormone important for regulating ovulation and menstruation. Norethindrone is used for birth control (contraception) to prevent pregnancy. Norethindrone is also used to treat menstrual disorders, endometriosis, or abnormal vaginal bleeding caused by a hormone imbalance. Not all brands of norethindrone are for the same uses. Some brands are for use only as contraception. Others are for use in treating endometriosis or vaginal bleeding disorders. Avoid medication errors by using only the brand, form, and strength your doctor prescribes. Norethindrone may also be used for other purposes not listed in this medication guide. Warnings You should not use this medicine if you you have: undiagnosed vaginal bleeding, breast cancer, liver disease, or a liver tumor. You may not be able to take norethindrone if you have ever had a heart attack, a stroke, or blood clot. Do not use if you are pregnant or trying to become pregnant. In some cases, you should not take norethindrone if you are nursing. Before taking this medicine You should not use norethindrone if you are allergic to it, or if you have: unusual vaginal bleeding that has not been checked by a doctor; liver disease or a liver tumor; breast cancer; or a history of blood clots in your brain, eyes, lungs, or legs. Do not use norethindrone if you are pregnant or trying to become pregnant. Stop taking the medicine and tell your doctor right away if you become pregnant. Ask your doctor about using norethindrone while you are breast-feeding. In some cases, you should not take norethindrone if you are nursing. Tell your doctor if you have ever had: heart disease, high blood pressure; liver disease; depression; migraine headaches; diabetes; high cholesterol or triglycerides; uterine fibroid tumors; epilepsy; kidney disease; asthma; or if you smoke. Do not give this medicine to a child without medical advice. How should I take norethindrone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Carefully follow your doctor's dosing instructions about when to start taking norethindrone for contraception if you are switching from a combination birth control pill (estrogen and progestin). If you take norethindrone for contraception: Take one pill every day, no more than 24 hours apart. You may get pregnant if you do not take one pill daily. You may need to use back-up birth control (such as condoms with spermicide) if you are sick with vomiting or diarrhea, or if you are 3 or more hours late in taking your daily dose. If you take norethindrone for menstrual disorders or abnormal vaginal bleeding: You will most likely take the medicine for only 5 to 10 days. Vaginal bleeding will occur 3 to 7 days after your last dose. If you take norethindrone for endometriosis: Norethindrone is usually taken daily long-term for several months. Your doctor may occasionally change your dose. Your doctor should check your progress on a regular basis. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms. Report any unusual vaginal bleeding right away. Norethindrone can affect the results of certain medical tests. Tell any doctor who treats you that you are using norethindrone. Store this medication at room temperature away from moisture, heat, and light. What happens if I miss a dose? Call your doctor for instructions, or follow the patient instructions provided with your medicine. Missing a birth control pill increases your risk of becoming pregnant. If you are more than 3 hours late for your dose, take the medicine as soon as you remember and use back-up birth control for at least 48 hours. Take your next pill at the regularly scheduled time and continue on your regular dosing schedule. If you miss a period for two months in a row, call your doctor because you might be pregnant. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of norethindrone is not expected to be dangerous. What should I avoid while taking norethindrone? Do not use estrogen medication unless your doctor tells you to. Avoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while taking norethindrone for contraception. Norethindrone will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases. Norethindrone side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: sudden vision loss, bulging eyes, or severe headache; swelling, rapid weight gain; unusual vaginal bleeding; missed menstrual periods; pelvic pain (especially on one side); a breast lump; a light-headed feeling, like you might pass out; increased thirst, increased urination; liver problems--loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes); or signs of a blood clot--sudden numbness or weakness, problems with vision or speech, chest pain, shortness of breath, swelling or redness in an arm or leg. Common side effects may include: irregular vaginal bleeding or spotting; headache; breast pain or swelling; stomach pain, bloating, nausea, vomiting; hair loss; depressed mood, trouble sleeping; weight gain; or vaginal itching or discharge. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Norethindrone dosing information Usual Adult Dose for Abnormal Uterine Bleeding: 2.5 to 10 mg orally once a day Duration of therapy: 5 to 10 days Comments: -This drug should be used when the endometrium is adequately primed with endogenous/exogenous estrogen. -Withdrawal bleeding typically occurs within 3 to 7 days of treatment discontinuation. Use: Treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance without organic pathology (e.g., submucous fibroids, uterine cancer) Usual Adult Dose for Amenorrhea: 2.5 to 10 mg orally once a day Duration of therapy: 5 to 10 days Comments: -This drug should be used when the endometrium is adequately primed with endogenous/exogenous estrogen. -Withdrawal bleeding typically occurs within 3 to 7 days of treatment discontinuation. Use: Treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance without organic pathology (e.g., submucous fibroids, uterine cancer) Usual Adult Dose for Contraception: 0.35 mg orally once a day Comment: -This drug should be taken at the same time each day. Use: Prevention of pregnancy Usual Adult Dose for Endometriosis: Initial dose: 5 mg orally once a day for 2 weeks -Maximum dose: 15 mg/day Comments: -The dose should be increased by 2.5 mg/day every 2 weeks until 15 mg is reached. -Treatment may continue for 6 to 9 months OR until annoying breakthrough bleeding demands temporary termination. Uses: Treatment of endometriosis Usual Pediatric Dose for Contraception: Postpubertal adolescents (under 16 years): 0.35 mg orally once a day Comments: -This drug should be used after menarche occurs. -The dose should be taken at the same time each day. Use: Prevention of pregnancy   What other drugs will affect norethindrone? Some drugs can make norethindrone less effective, which may result in unintended pregnancy if you use norethindrone for contraception. Tell your doctor about all your other medicines, especially: St. John's wort; medicine to treat an infection (antibiotics or antifungal medicine); medicine to treat tuberculosis; medicine to treat HIV or AIDS; or seizure medication. This list is not complete. Other drugs may affect norethindrone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is norethindrone? Norethindrone is a form of progesterone, a female hormone important for regulating ovulation and menstruation. Norethindrone is used for birth control (contraception) to prevent pregnancy. Norethindrone is also used to treat menstrual disorders, endometriosis, or abnormal vaginal bleeding caused by a hormone imbalance. Not all brands of norethindrone are for the same uses. Some brands are for use only as contraception. Others are for use in treating endometriosis or vaginal bleeding disorders. Avoid medication errors by using only the brand, form, and strength your doctor prescribes. Norethindrone may also be used for other purposes not listed in this medication guide. Warnings You should not use this medicine if you you have: undiagnosed vaginal bleeding, breast cancer, liver disease, or a liver tumor. You may not be able to take norethindrone if you have ever had a heart attack, a stroke, or blood clot. Do not use if you are pregnant or trying to become pregnant. In some cases, you should not take norethindrone if you are nursing. Before taking this medicine You should not use norethindrone if you are allergic to it, or if you have: unusual vaginal bleeding that has not been checked by a doctor; liver disease or a liver tumor; breast cancer; or a history of blood clots in your brain, eyes, lungs, or legs. Do not use norethindrone if you are pregnant or trying to become pregnant. Stop taking the medicine and tell your doctor right away if you become pregnant. Ask your doctor about using norethindrone while you are breast-feeding. In some cases, you should not take norethindrone if you are nursing. Tell your doctor if you have ever had: heart disease, high blood pressure; liver disease; depression; migraine headaches; diabetes; high cholesterol or triglycerides; uterine fibroid tumors; epilepsy; kidney disease; asthma; or if you smoke. Do not give this medicine to a child without medical advice. How should I take norethindrone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Carefully follow your doctor's dosing instructions about when to start taking norethindrone for contraception if you are switching from a combination birth control pill (estrogen and progestin). If you take norethindrone for contraception: Take one pill every day, no more than 24 hours apart. You may get pregnant if you do not take one pill daily. You may need to use back-up birth control (such as condoms with spermicide) if you are sick with vomiting or diarrhea, or if you are 3 or more hours late in taking your daily dose. If you take norethindrone for menstrual disorders or abnormal vaginal bleeding: You will most likely take the medicine for only 5 to 10 days. Vaginal bleeding will occur 3 to 7 days after your last dose. If you take norethindrone for endometriosis: Norethindrone is usually taken daily long-term for several months. Your doctor may occasionally change your dose. Your doctor should check your progress on a regular basis. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms. Report any unusual vaginal bleeding right away. Norethindrone can affect the results of certain medical tests. Tell any doctor who treats you that you are using norethindrone. Store this medication at room temperature away from moisture, heat, and light. What happens if I miss a dose? Call your doctor for instructions, or follow the patient instructions provided with your medicine. Missing a birth control pill increases your risk of becoming pregnant. If you are more than 3 hours late for your dose, take the medicine as soon as you remember and use back-up birth control for at least 48 hours. Take your next pill at the regularly scheduled time and continue on your regular dosing schedule. If you miss a period for two months in a row, call your doctor because you might be pregnant. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of norethindrone is not expected to be dangerous. What should I avoid while taking norethindrone? Do not use estrogen medication unless your doctor tells you to. Avoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while taking norethindrone for contraception. Norethindrone will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases. Norethindrone side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: sudden vision loss, bulging eyes, or severe headache; swelling, rapid weight gain; unusual vaginal bleeding; missed menstrual periods; pelvic pain (especially on one side); a breast lump; a light-headed feeling, like you might pass out; increased thirst, increased urination; liver problems--loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes); or signs of a blood clot--sudden numbness or weakness, problems with vision or speech, chest pain, shortness of breath, swelling or redness in an arm or leg. Common side effects may include: irregular vaginal bleeding or spotting; headache; breast pain or swelling; stomach pain, bloating, nausea, vomiting; hair loss; depressed mood, trouble sleeping; weight gain; or vaginal itching or discharge. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Norethindrone dosing information Usual Adult Dose for Abnormal Uterine Bleeding: 2.5 to 10 mg orally once a day Duration of therapy: 5 to 10 days Comments: -This drug should be used when the endometrium is adequately primed with endogenous/exogenous estrogen. -Withdrawal bleeding typically occurs within 3 to 7 days of treatment discontinuation. Use: Treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance without organic pathology (e.g., submucous fibroids, uterine cancer) Usual Adult Dose for Amenorrhea: 2.5 to 10 mg orally once a day Duration of therapy: 5 to 10 days Comments: -This drug should be used when the endometrium is adequately primed with endogenous/exogenous estrogen. -Withdrawal bleeding typically occurs within 3 to 7 days of treatment discontinuation. Use: Treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance without organic pathology (e.g., submucous fibroids, uterine cancer) Usual Adult Dose for Contraception: 0.35 mg orally once a day Comment: -This drug should be taken at the same time each day. Use: Prevention of pregnancy Usual Adult Dose for Endometriosis: Initial dose: 5 mg orally once a day for 2 weeks -Maximum dose: 15 mg/day Comments: -The dose should be increased by 2.5 mg/day every 2 weeks until 15 mg is reached. -Treatment may continue for 6 to 9 months OR until annoying breakthrough bleeding demands temporary termination. Uses: Treatment of endometriosis Usual Pediatric Dose for Contraception: Postpubertal adolescents (under 16 years): 0.35 mg orally once a day Comments: -This drug should be used after menarche occurs. -The dose should be taken at the same time each day. Use: Prevention of pregnancy   What other drugs will affect norethindrone? Some drugs can make norethindrone less effective, which may result in unintended pregnancy if you use norethindrone for contraception. Tell your doctor about all your other medicines, especially: St. John's wort; medicine to treat an infection (antibiotics or antifungal medicine); medicine to treat tuberculosis; medicine to treat HIV or AIDS; or seizure medication. This list is not complete. Other drugs may affect norethindrone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is ethinyl estradiol and norethindrone? Ethinyl estradiol is a form of estrogen. Estrogen is a female sex hormone necessary for many processes in the body. Norethindrone is a form of progesterone. Progesterone is a female hormone important for the regulation of ovulation and menstruation. Ethinyl estradiol and norethindrone HRT (hormone replacement therapy) is a combination medicine used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. It is also used to prevent osteoporosis. Ethinyl estradiol and norethindrone may also be used for purposes not listed in this medication guide. Warnings You should not use ethinyl estradiol and norethindrone if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, if you will have major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina. Do not use if you are pregnant. This medicine may increase your risk of developing a condition that may lead to uterine cancer. Report any unusual vaginal bleeding right away. Using this medicine can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, or ovaries. Ethinyl estradiol and norethindrone should not be used to prevent heart disease, stroke, or dementia. Before taking this medicine You should not use this medicine if you are allergic to ethinyl estradiol or norethindrone, or if you have: unusual vaginal bleeding that has not been checked by a doctor; liver disease; a bleeding disorder; a history of heart attack, stroke, or blood clot; or a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina. Do not use if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Using this medicine can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, if you are overweight, or if you smoke. Ethinyl estradiol and norethindrone should not be used to prevent heart disease, stroke, or dementia, because this medicine may actually increase your risk of developing these conditions. Tell your doctor if you have ever had: heart disease; liver problems, or jaundice caused by pregnancy or taking hormones; kidney disease; hereditary angioedema (an immune system disorder); bone cancer; lupus; asthma; epilepsy or other seizure disorder; migraines; porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system); gallbladder disease; endometriosis or uterine fibroid tumors; a thyroid disorder; or high or low levels of calcium in your blood. Using ethinyl estradiol and norethindrone may increase your risk of cancer of the breast, uterus, or ovaries. Talk with your doctor about this risk. This medicine can slow breast milk production. Tell your doctor if you are breast-feeding. How should I take ethinyl estradiol and norethindrone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Try to take ethinyl estradiol and norethindrone at the same time each day. Ethinyl estradiol and norethindrone may increase your risk of developing a condition that can lead to uterine cancer. To help lower this risk, your doctor may also want you to take a progestin. Report any unusual vaginal bleeding right away. Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms. If you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using ethinyl estradiol and norethindrone. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, or vaginal bleeding. What should I avoid while taking ethinyl estradiol and norethindrone? Avoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while using ethinyl estradiol and norethindrone. Grapefruit may interact with ethinyl estradiol and norethindrone and lead to unwanted side effects. Avoid the use of grapefruit products. Ethinyl estradiol and norethindrone side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have: heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed; signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance; signs of a blood clot--sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs; swelling or tenderness in your stomach; jaundice (yellowing of the skin or eyes); unusual vaginal bleeding, pelvic pain; a breast lump; memory problems, confusion, unusual behavior; or high levels of calcium in your blood--nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, lack of energy. Common side effects may include: stomach pain; bloating, swelling, weight gain; breast pain; light vaginal bleeding or spotting; thinning scalp hair; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Ethinyl estradiol and norethindrone dosing information Usual Adult Dose for Contraception: 1 tablet orally once a day Comments: To be taken at the same time each day. Usual Adult Dose for Postmenopausal Symptoms: 1 tablet orally once a day Comments: Not all preparations are indicated for the treatment of vasomotor symptoms due to menopause; the manufacturer product information should be consulted. Use: For the treatment of moderate to severe vasomotor symptoms due to menopause Usual Adult Dose for Acne: 1 tablet orally once a day Comments: Not all preparations are indicated for the treatment of acne; the manufacturer product information should be consulted. Use: For the treatment of moderate acne vulgaris in females with no known contraindications to oral contraceptive therapy and who have achieved menarche and are unresponsive to topical anti-acne medications Usual Adult Dose for Prevention of Osteoporosis: 1 tablet orally once a day Comments: -Not all preparations are indicated for the prevention of postmenopausal osteoporosis; the manufacturer product information should be consulted. -When prescribing solely for the prevention of postmenopausal osteoporosis, therapy should only be considered for women at significant risk of osteoporosis and non-estrogen medication should be carefully considered. Use: For the prevention of postmenopausal osteoporosis Usual Pediatric Dose for Contraception: 1 tablet orally once a day Comments: To be taken at the same time each day. Usual Pediatric Dose for Acne: 15 years or older: 1 tablet orally once a day Comments: -Not all preparations are indicated for the treatment of acne; the manufacturer product information should be consulted. -Use should be reserved for the treatment of acne only if the patient desires an oral contraceptive for birth control and plans to stay on it for at least 6 months Use: For the treatment of moderate acne vulgaris in females at least 15 years of age with no known contraindications to oral contraceptive therapy and who have achieved menarche and are unresponsive to topical anti-acne medications   What other drugs will affect ethinyl estradiol and norethindrone? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Other drugs may affect ethinyl estradiol and norethindrone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is nortriptyline? Nortriptyline is a tricyclic antidepressant. It affects chemicals in the brain that may be unbalanced in people with depression. Nortriptyline is used to treat symptoms of depression. Nortriptyline is not recommended for use in children. Warnings You should not use nortriptyline if you recently had a heart attack. Do not use nortriptyline if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine and others. Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Before taking this medicine You should not use nortriptyline if: you are allergic to it or similar medicines (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, protriptyline, trimipramine); you are allergic to certain seizure medications (carbamazepine, eslicarbazepine, oxcarbazepine, rufinamide); or you recently had a heart attack. Do not use nortriptyline if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others. Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with nortriptyline could cause a serious condition called serotonin syndrome. Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. To make sure nortriptyline is safe for you, tell your doctor if you have ever had: unexplained fainting spells; a genetic heart condition called Brugada syndrome; a family history of unexplained death at younger than 45 years old; heart disease; a heart attack or stroke; a seizure; bipolar disorder (manic-depression); schizophrenia or other mental illness; a thyroid disorder; problems with urination; narrow-angle glaucoma; or if you are receiving electroshock treatment. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Tell your doctor if you are pregnant or breastfeeding. Nortriptyline is not approved for use by anyone younger than 18 years old. How should I take nortriptyline? Take nortriptyline exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). If you need surgery, tell your surgeon you currently use nortriptyline. You may need to stop for a short time. You may have unpleasant withdrawal symptoms if you stop using nortriptyline suddenly. Ask your doctor how to safely stop using this medicine. It may take a few weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Dosing information Usual Adult Dose for Depression: 25 mg orally 3 to 4 times per day -Maximum dose: 150 mg/day Comments: -The total daily dosage may be given once a day. -Patients should be started at lower doses, and the doses should be gradually increased. -When doses above 100 mg per day are given, plasma levels should be monitored and maintained in the optimum range of 50 to 150 ng/mL. Use: Relief of symptoms of depression Usual Geriatric Dose for Depression: 30 to 50 mg orally per day, in divided doses Comments: -The total daily dosage may be given once a day. -Patients should be started at lower doses, and the doses should be gradually increased. Use: Relief of symptoms of depression   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of nortriptyline can be fatal. Overdose symptoms may include irregular heartbeats, severe drowsiness, vision problems, confusion, hallucinations, agitation, stiff muscles, overactive reflexes, vomiting, feeling hot or cold, feeling like you might pass out, seizures, or coma. What to avoid Do not drink alcohol. Dangerous side effects or death could occur. Avoid driving or hazardous activity until you know how nortriptyline will affect you. Your reactions could be impaired. Nortriptyline could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Nortriptyline side effects Get emergency medical help if you have signs of an allergic reaction to nortriptyline: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights; restless muscle movements in your eyes, tongue, jaw, or neck; a light-headed feeling, like you might pass out; seizure (convulsions); new or worsening chest pain, pounding heartbeats or fluttering in your chest; sudden numbness or weakness, problems with vision, speech, or balance; fever, sore throat, easy bruising, unusual bleeding; painful or difficult urination; or jaundice (yellowing of the skin or eyes). Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Common nortriptyline side effects may include: increased blood pressure; numbness or tingling in your hands or feet; dry mouth, nausea, vomiting, loss of appetite; blurred vision; rash, itching; or breast swelling (in men or women). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect nortriptyline? Using nortriptyline with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: medicine to treat depression, anxiety, mood disorders, or mental illness; cold or allergy medicine (Benadryl, Sudafed, and others); a stimulant medicine, such as diet pills or ADHD medicine; medicine to treat Parkinson's disease; medicine to treat stomach problems, motion sickness, or irritable bowel syndrome; medicine to treat overactive bladder; or bronchodilator asthma medication. This list is not complete. Other drugs may interact with nortriptyline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is Nyamyc? Nystatin is an antifungal medication. Nystatin prevents fungus from growing on your skin. Nyamyc (for the skin) is used to treat skin infections caused by yeast. Nyamyc is not for use to treat a vaginal yeast infection. Nyamyc may also be used for purposes not listed in this medication guide. Warnings Do not use Nyamyc to treat any skin condition that has not been checked by your doctor. Nyamyc (for the skin) is not for use to treat a vaginal yeast infection. Avoid getting this medication in your eyes or mouth. If this does happen, rinse with water. Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Call your doctor if your symptoms do not improve, or if they get worse while using Nyamyc. Do not share this medication with another person, even if they have the same symptoms you have. Before taking this medicine You should not use Nyamyc if you have ever had an allergic reaction to it. FDA pregnancy category C. It is not known whether Nyamyc will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether nystatin topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I use Nyamyc? Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Do not use Nyamyc to treat any skin condition that has not been checked by your doctor. Wash your hands before and after using this medication. Clean and dry the skin before you apply Nyamyc. Do not cover treated skin with bandages or dressings that do not allow air circulation unless your doctor tells you to. Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Call your doctor if your symptoms do not improve, or if they get worse while using Nyamyc. Do not share this medication with another person, even if they have the same symptoms you have. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using Nyamyc? Avoid getting this medication in your eyes or mouth. If this does happen, rinse with water. Avoid wearing tight-fitting, synthetic clothing (such as nylon) that doesn't allow air circulation. Wear clothing made of loose cotton and other natural fibers until your infection is healed. Nyamyc side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Nyamyc and call your doctor at once if you have severe burning, itching, rash, pain, or other irritation where the medicine is applied. Less serious side effects may include mild itching or irritation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect Nyamyc? It is not likely that other drugs you take orally or inject will have an effect on topically applied Nyamyc. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

What is nystatin topical? Nystatin is an antifungal medication. Nystatin prevents fungus from growing on your skin. Nystatin topical (for the skin) is used to treat skin infections caused by yeast. Nystatin topical is not for use to treat a vaginal yeast infection. Nystatin topical may also be used for purposes not listed in this medication guide. Warnings Do not use nystatin topical to treat any skin condition that has not been checked by your doctor. Nystatin topical (for the skin) is not for use to treat a vaginal yeast infection. Avoid getting this medication in your eyes or mouth. If this does happen, rinse with water. Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Call your doctor if your symptoms do not improve, or if they get worse while using nystatin topical. Do not share this medication with another person, even if they have the same symptoms you have. Before taking this medicine You should not use nystatin topical if you have ever had an allergic reaction to it. FDA pregnancy category C. It is not known whether nystatin topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether nystatin topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I use nystatin topical? Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Do not use nystatin topical to treat any skin condition that has not been checked by your doctor. Wash your hands before and after using this medication. Clean and dry the skin before you apply nystatin topical. Do not cover treated skin with bandages or dressings that do not allow air circulation unless your doctor tells you to. Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Call your doctor if your symptoms do not improve, or if they get worse while using nystatin topical. Do not share this medication with another person, even if they have the same symptoms you have. Store at room temperature away from moisture and heat. What happens if I miss a dose? Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using nystatin topical? Avoid getting this medication in your eyes or mouth. If this does happen, rinse with water. Avoid wearing tight-fitting, synthetic clothing (such as nylon) that doesn't allow air circulation. Wear clothing made of loose cotton and other natural fibers until your infection is healed. Nystatin topical side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using nystatin topical and call your doctor at once if you have severe burning, itching, rash, pain, or other irritation where the medicine is applied. Less serious side effects may include mild itching or irritation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Nystatin topical dosing information Usual Adult Dose for Cutaneous Candidiasis: Apply nystatin topical cream, ointment or powder in a quantity sufficient to cover the affected area and immediately surrounding skin 2 to 4 times a day. The powder formulation is useful for the treatment of moist areas or lesions. Therapy should be continued for 2 to 8 weeks, depending on the nature and severity of the infection. Usual Adult Dose for Vaginal Candidiasis: Insert one nystatin vaginal tablet (100,000 units) vaginally once a day, preferably at bedtime, for a total of 14 days. Usual Pediatric Dose for Cutaneous Candidiasis: Apply nystatin topical cream, ointment or powder in a quantity sufficient to cover the affected area and immediately surrounding skin 2 to 4 times a day. The powder formulation is useful for the treatment of moist areas or lesions. Therapy should be continued for 2 to 8 weeks, depending on the nature and severity of the infection. Usual Pediatric Dose for Vaginal Candidiasis: >13 <18 years: Insert one nystatin vaginal tablet (100,000 units) vaginally once a day, preferably at bedtime, for a total of 14 days.  

What is nystatin and triamcinolone? Nystatin is an antifungal medicine. Triamcinolone is a steroid medicine. Nystatin and triamcinolone topical (for the skin) is a combination medicine used to treat skin infections caused by fungus or yeast. Nystatin and triamcinolone topical may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use nystatin and triamcinolone if you are allergic to nystatin or triamcinolone. Tell your doctor if you have ever had: any type of skin infection; a skin reaction to any steroid medicine; liver disease; or an adrenal gland disorder. Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply this medicine to your chest, avoid areas that may come into contact with the baby's mouth. Do not use this medicine on a child without medical advice. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects. How should I use nystatin and triamcinolone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Do not take by mouth. This medicine is for use only on the skin. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Wash your hands before and after using nystatin and triamcinolone, unless you are using this medicine to treat the skin on your hands. Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to. Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects. If you are treating the diaper area, do not use plastic pants or tight-fitting diapers. Call your doctor if your skin condition does not improve after 25 days of treatment, or if it gets worse while using this medicine. You should stop using this medicine once your skin symptoms are controlled. You should not stop using nystatin and triamcinolone suddenly. Follow your doctor's instructions about tapering your dose. Store at room temperature away from moisture and heat. Do not freeze. Keep the tube tightly closed when not in use. What happens if I miss a dose? Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. High doses or long-term use of nystatin and triamcinolone topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using nystatin and triamcinolone? Avoid getting nystatin and triamcinolone in your eyes. Do not use nystatin and triamcinolone topical to treat any skin condition that has not been checked by your doctor. Nystatin and triamcinolone side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening of your skin condition; redness, warmth, swelling, oozing, or severe irritation of any treated skin; high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes. Common side effects may include: burning, itching, or irritation of treated skin; increased hair growth; white or "pruned" appearance of the skin; rash, pimples; or changes in color of treated skin. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Nystatin and triamcinolone dosing information Usual Adult Dose for Cutaneous Candidiasis: Cream: Apply to affected areas twice a day (morning and evening). Ointment: Apply a thin film to affected areas twice a day (morning and evening). Use: For the treatment of cutaneous candidiasis Usual Pediatric Dose for Cutaneous Candidiasis: 2 months or older: -Cream: Apply to affected areas twice a day (morning and evening). -Ointment: Apply a thin film to affected areas twice a day (morning and evening). Use: For the treatment of cutaneous candidiasis   What other drugs will affect nystatin and triamcinolone? Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.