GGT

"Clinical Significance
Gamma Glutamyl Transferase (GGT) - Elevated GGT is found in all forms of liver disease. Measurement of GGT is used in the diagnosis and treatment of alcoholic cirrhosis, as well as primary and secondary liver tumors. It is more sensitive than alkaline phosphatase, the transaminases, and leucine aminopeptidase in detecting obstructive jaundice, cholangitis, and cholecystitis. Normal levels of GGT are seen in skeletal diseases; thus, GGT in serum can be used to ascertain whether a disease, suggested by elevated alkaline phosphatase, is skeletal or hepatobiliary.

Preferred Specimen(s)
1 mL serum

Minimum Volume
0.5 mL

Transport Container
Serum Separator Tube (SST®)

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria
Plasma

Setup Schedule"

Methodology
Spectrophotometry (SP)

Reference Range(s)
     Male (U/L)    Female (U/L)
<6 Months    12-122    15-132
6-11 Months     ≤39     ≤39
1-12 Years    3-22    3-22
13-15 Years    8-32    7-18
16-19 Years    9-31    6-26
20-29 Years    3-70    3-40
30-39 Years    3-90    3-50
40-54 Years    3-95     
40-49 Years         3-55
50-59 Years         3-70
55-59 Years    3-85     
≥60 Years    3-70    3-65

Alternative Name(s)
GGT